Product Manager, AI Platform & Partnerships

Summary

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening. They are seeking a Product Manager to lead the roadmap for AI projects, translating ambitious ideas into internal products and nurturing relationships with external AI partners.

Responsibilities

• Define the product vision, roadmap, and success metrics for Manifold’s AI platform capabilities, including protein design, foundation models, and agents
• Translate internal R&D and AI x biology ideas into concrete requirements and run the operating cadences that drive decisions and accountability
• Own Manifold's strategy for engaging the AI ecosystem; decide which partners to prioritize, what to build with each, and how to sequence engagements
• Coordinate cross-functional execution across AI/ML, protein engineering, biology, and platform teams for partnerships and platform development
• Source, qualify, and close new AI partnership opportunities, leading exploratory conversations through to signed scope
• Own the quality of all external deliverables including reports, decks, and demos, and produce executive-ready memos to align internal stakeholders

Skills

• 2+ years of product management, technical program management, alliance management, or BD experience, with at least part of that in AI/ML or computational product environments
• Bachelor's degree in a technical field (CS, engineering, biology, or related); advanced degree a plus
• Demonstrated ability to own complex, ambiguous strategic relationships and drive them to concrete value generating outcomes
• Strong working knowledge of modern AI/ML concepts (foundation models, training and evaluation, agentic systems, scaling laws) and how they apply to scientific and industrial problems specific to drug discovery
• Familiarity with biology, protein engineering, drug discovery, or another applied scientific domain
• Exceptional written communication; ability to produce executive-ready memos, decks, and external deliverables independently
• Track record of running cross-functional execution in matrixed organizations and shipping on aggressive timelines
• Comfort operating in high-ambiguity, fast-evolving partnerships where the product itself is being defined as you go
• Demonstrated handle of agentic coding skills; e.g. ability to rapidly run analyses / generate figures
• Experience building or shipping products at a frontier AI lab, AI infrastructure company, or AI-first startup
• Experience structuring partnership terms in collaboration with BD and legal (data rights, IP, joint roadmaps)
• Public writing, talks, or other evidence of unusually strong communication ability
• Experience scaling a partnership function or building partnership operating processes from scratch

Qualifications

Must Haves

• 2+ years of product management, technical program management, alliance management, or BD experience, with at least part of that in AI/ML or computational product environments
• Bachelor's degree in a technical field (CS, engineering, biology, or related); advanced degree a plus
• Demonstrated ability to own complex, ambiguous strategic relationships and drive them to concrete value generating outcomes
• Strong working knowledge of modern AI/ML concepts (foundation models, training and evaluation, agentic systems, scaling laws) and how they apply to scientific and industrial problems specific to drug discovery
• Familiarity with biology, protein engineering, drug discovery, or another applied scientific domain
• Exceptional written communication; ability to produce executive-ready memos, decks, and external deliverables independently
• Track record of running cross-functional execution in matrixed organizations and shipping on aggressive timelines
• Comfort operating in high-ambiguity, fast-evolving partnerships where the product itself is being defined as you go
• Demonstrated handle of agentic coding skills; e.g. ability to rapidly run analyses / generate figures

Nice to Haves

• Experience building or shipping products at a frontier AI lab, AI infrastructure company, or AI-first startup
• Experience structuring partnership terms in collaboration with BD and legal (data rights, IP, joint roadmaps)
• Public writing, talks, or other evidence of unusually strong communication ability
• Experience scaling a partnership function or building partnership operating processes from scratch